Lex H T Van der Ploeg Selected Research

Heart Failure

5/2004

Crystal structure of human phosphodiesterase 3B: atomic basis for substrate and inhibitor specificity.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Lex H T Van der Ploeg Research Topics

Disease

13	Body Weight (Weight, Body) 01/2018 - 04/2002
9	Obesity 01/2018 - 04/2002
2	Weight Gain 08/2021 - 06/2007
2	Inflammation (Inflammations) 08/2021 - 05/2004
2	Weight Loss (Weight Reduction) 10/2017 - 06/2007
1	Edema (Dropsy) 08/2021
1	Fibrosis (Cirrhosis) 08/2021
1	Non-alcoholic Fatty Liver Disease 08/2021
1	Morbid Obesity 01/2018
1	Neoplasms (Cancer) 03/2015
1	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL) 04/2009
1	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 04/2009
1	Insulin Resistance 07/2008
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2006
1	Tics (Tic) 10/2005
1	Cachexia 04/2005
1	Alzheimer Disease (Alzheimer's Disease) 10/2004
1	Amyloidosis 10/2004
1	Heart Failure 05/2004
1	Erectile Dysfunction 05/2004
1	Hyperphagia (Overeating) 05/2003
1	Hyperinsulinism (Hyperinsulinemia) 05/2003
1	Hypercholesterolemia 05/2003
1	Ganglion Cysts (Ganglion) 08/2002
1	Starvation 07/2002

Drug/Important Bio-Agent (IBA)

5	Type 4 Melanocortin Receptor (Melanocortin-4 Receptor)IBA 01/2018 - 01/2006
3	Peptides (Polypeptides)IBA 10/2017 - 08/2002
3	setmelanotideIBA 10/2017 - 03/2015
3	Neuropeptide YIBA 05/2006 - 07/2002
3	MelanocortinsIBA 10/2005 - 04/2002
2	CholesterolIBA 08/2021 - 03/2015
2	Pharmaceutical PreparationsIBA 08/2021 - 01/2006
2	DeuteriumIBA 08/2021 - 03/2015
2	Leptin ReceptorsIBA 01/2018 - 05/2006
2	Pro-Opiomelanocortin (Proopiomelanocortin)IBA 01/2018 - 10/2017
2	neuropeptide Y5 receptorIBA 05/2006 - 05/2003
2	NeuropeptidesIBA 01/2006 - 07/2002
1	Pioglitazone (Actos)FDA Link 08/2021
1	Nonesterified Fatty Acids (NEFA)IBA 08/2021
1	Glucose (Dextrose)FDA LinkGeneric 08/2021
1	Hypoglycemic Agents (Hypoglycemics)IBA 08/2021
1	Triglycerides (Triacylglycerol)IBA 08/2021
1	Monocarboxylic Acid TransportersIBA 08/2021
1	PPAR gammaIBA 08/2021
1	Proprotein Convertase 1IBA 01/2018
1	HydrogenIBA 03/2015
1	Thalidomide (Thalomid)FDA Link 03/2015
1	3- (5- amino- 2- methyl- 4- oxoquinazolin- 3(4H)- yl)piperidine- 2,6- dioneIBA 03/2015
1	Liraglutide FDA Link 03/2015
1	Glucagon-Like Peptide-1 ReceptorIBA 03/2015
1	Notch ReceptorsIBA 04/2009
1	Gamma Secretase Inhibitors and ModulatorsIBA 04/2009
1	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 04/2009
1	Spironolactone (Aldactone)FDA LinkGeneric 07/2008
1	sibutramine (Meridia)FDA Link 07/2008
1	Insulin (Novolin)FDA Link 07/2008
1	N- (3- (4- chlorophenyl)- 2- (3- cyanophenyl)- 1- methylpropyl)- 2- methyl- 2- ((5- (trifluoromethyl)pyridin- 2- yl)oxy)propanamideIBA 06/2007
1	melanin-concentrating hormone receptorIBA 04/2005
1	AmidesIBA 03/2005
1	CB1 Cannabinoid Receptor (CB1 Receptor)IBA 03/2005
1	Amyloid beta-PeptidesIBA 10/2004
1	Proteins (Proteins, Gene)FDA Link 10/2004
1	Flavin-Adenine Dinucleotide (FAD)IBA 10/2004
1	Cyclic NucleotidesIBA 05/2004
1	EnzymesIBA 05/2004
1	Phosphoric Diester Hydrolases (Phosphodiesterases)IBA 05/2004
1	diethylstilbestrol monophosphate (PDES)IBA 05/2004
1	LeptinIBA 07/2002
1	Agouti-Related ProteinIBA 07/2002

Therapy/Procedure

3	Therapeutics 03/2015 - 01/2006
1	Glycemic Control 03/2015
1	Lasers (Laser) 10/2004
1	Oral Administration 05/2003
1	Intraventricular Infusions 05/2003